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Environmental strains of Enterococcus faecium with inducible high-level resistance to glycopeptides

I. Klare, H. Heier, H. Claus, W. Witte
DOI: http://dx.doi.org/10.1111/j.1574-6968.1993.tb05930.x 23-29 First published online: 1 January 1993


High-level resistance to glycopeptides in Enterococcus faecium is associated with an inducible 39-kDa cytoplasmic membrane protein. The present paper shows that such glycopeptide-resistant E. faecium strains can not only be isolated in a definite clinical setting but also from waste water of sewage treatment plants. Nearer characterization of these and of clinical isolates by resistance pattern, biotyping, and genotyping (DNA-fingerprinting with pulsed-field get electrophoresis) has shown that different glycopeptide-resistant E. faecium strains have been isolated from clinical sources and from waste water.

Key words
  • Glycopeptide resistance mechanism
  • Environmental Enterococcus faecium

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