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The flagellin gene of Borrelia miyamotoi sp. nov. and its phylogenetic relationship among Borrelia species

Masahito Fukunaga , Yasuyo Koreki
DOI: http://dx.doi.org/10.1111/j.1574-6968.1995.tb07947.x 255-258 First published online: 1 December 1995


We have cloned and sequenced the flagellin gene from Borrelia miyamotoi strain HT31 and compared it with previously published flagellin sequences. Sequence similarity analysis demonstrated that strain HT31 is phylogenetically distant from the three species of Lyme disease borreliae and is deeply branched into the relapsing fever borrelia cluster. The result was in full agreement with the classification of Borrelia strains using 16S rRNA sequences. This finding indicates that a phylogenetic analysis using flagellin gene sequences might be useful for classification of Borrelia strains.

  • Borrelia miyamotoi
  • Spirochete
  • Flagellin gene
  • Phylogeny

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