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Proline reduction by Clostridium sporogenes is coupled to vectorial proton ejection

Robert W. Lovitt, Douglas B. Kell, J.Gareth Morris
DOI: http://dx.doi.org/10.1111/j.1574-6968.1986.tb01708.x 269-273 First published online: 1 September 1986


The reduction of proline by Clostridium sporogenes NCIB8053 is coupled to transmembrane proton translocation in an uncoupler-sensitive fashion (and might therefore conserve free energy). This finding serves to explain the increase in the growth yield of this organism when proline is added to a defined growth medium containing glucose as the catabolic substrate.

  • Clostridium sporogenes
  • Stickland reaction
  • proline reductase
  • proton pump

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